Different manufacturers generally offer the same thing, for the most part. For defense, you are usually talking less than 15' from your target, so you want a bullet that will knock the subject down,(heavy bullet), and one that won't go thru with the potential for bad effects on the other side. So a frangible or heavy spreading hollow point. And it must work in your gun, which is the most important. Not all guns will feed all ammo, test it. For best results, practice with what you carry. Don't practice with light target loads and then get surprised by the power of that defense load. It may be expensive, if you don't reload, but there will be no surprises to you, if the time comes.