Just want to add that I have never, ever had a problem with the 42 jamming but I won't shoot junk either. As far as firepower of the 42 and 43, ask Chris. He'll tell you it's not the caliber of the gun but the bullet you put in it, as there is devastating 380 ammo and penetrates.
That said 380 ammo is more expensive than 9mm so practice with a 22 if that is your concern.
I was hesitant on the 380 until I loaded it with Liberty 50 gr 1500fps Civil Defense. You watch me shoot this in some jelly and you got to pay for the whole seat but you'll only need the edge of it! It will FUU.